Table 2.
Statistical results (F and p values) and group numbers (n) for Experiment 2. Factorial ANOVA and Newman-Keuls post-hoc tests were used to evaluate changes in PD24 gene expression following immediate shock training as a function of context exposures on the preexposure day (single vs multiple-exposures).
| Experiment 2: Single v Multiple- Exposure CPFE Training day Egr-1 expression PD24 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| AC | PL | IL | |||||||
| n (HC, Pre, Alt-Pre) | n (HC, Pre, Alt-Pre) | n (HC, Alt-Pre, Pre) | |||||||
|
|
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| SE PD 24 | 3, 10, 8 | 3, 10***, 8*** | 3, 10, 7 | ||||||
| ME PD 24 | 4, 8**, 8*** | 3, 8***, 7*** | 3, 7**, 8*** | ||||||
| F | p | F | p | F | p | ||||
|
|
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| Exposure | 10.07 | <.01 | ME>SE | 5.72 | 0.02 | ME>SE | 8.77 | <.01 | ME>SE |
|
|
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| Pre Condition | 12.55 | <.001 | Pre, Alt-Pre >HC | 12.27 | <.001 | Pre, Alt-Pre > HC | 15.70 | <.001 | Pre > Alt-Pre > HC |
|
|
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| Exposure x Pre Condition | 3.28 | 0.049 | ME Pre > all others | 1.57 | 0.22 | NS | 4.74 | 0.02 | ME Pre > all others |
|
| |||||||||
| OFC | dHPC | dLA | |||||||
| n (HC, Pre, Alt-Pre) | n (HC, Pre, Alt-Pre) | n (HC, Alt-Pre, Pre) | |||||||
|
|
|||||||||
| SE PD 24 | 3.9***, 7*** | 5, 9, 6 | 4, 10***, 5*** | ||||||
| ME PD 24 | 3.8 ***, 8*** | 3, 7, 8 | 5, 8***, 9*** | ||||||
| F | p | F | p | F | p | ||||
|
|
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| Exposure | 5.38 | 0.03 | SE>ME | 6.23 | 0.02 | SE>ME | 0.94 | 0.34 | NS |
|
|
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| Pre Condition | 11.43 | <.001 | Pre > Alt-Pre > HC | 0.82 | 0.45 | NS | 9.03 | <.001 | Pre, Alt-Pre > HC |
|
|
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| Exposure x Pre Condition | 2.66 | 0.09 | NS | 1.54 | 0.23 | NS | 2.2 | 0.13 | NS |
Asterisks (next to group n) represent Newman-Keuls post hoc tests comparing experimental groups to homecage (HC) controls.
*
p < .05,
**
p < .01,
***
p < .001.
Main or interaction effects are described by inequality signs (> or <) and non-significant effects are listed as “NS.”