Skip to main content
. Author manuscript; available in PMC: 2019 Apr 15.
Published in final edited form as: J Immunol. 2018 Mar 7;200(8):2894–2904. doi: 10.4049/jimmunol.1701499

Figure 2. Intact early activation, proliferation, poly-functionality and differentiation of CD8 T cells in the absence of LIGHT.

Figure 2

Mice that received WT or LIGHT−/− CD8 T cells in Fig 1 were analyzed on day 6 and 8 post-infection. (A-E) Lung cells were stained extracellularly with antibodies to CD8, Vα2, Vβ5, CD44, CD25, CD69, CXCR3, CD62L, IL7Rα (CD127); (B) intranuclearly with Ki67; (C) intracellularly with antibodies to TNF, IFNγ following re-stimulation with SIINFEKL peptide during which CD107α was added; and (D) intra-nuclearly with antibodies to t-bet, eomes, blimp1, pStat5, without peptide re-stimulation.