Fig. 2.

Crystal structure of Heligmosomoides polygyrus Venom Allergen-like Protein-4 (HpVAL-4). (A) Cartoon of a monomer of HpVAL-4 rainbow colours from amino (blue) to carboxyl terminus (red). The two longest helices α1 and α3 that form the palmitate cavity and the caveolin binding motif loop are indicated, while glycans and disulfide bridges are shown in stick form (coloured by elements: blue for N, white for C, red for O, and yellow for S). (B) Rotation (180 degrees) of the monomer allows better visualisation of the strand (β1) and helix (α4) that form the central cavity. (C, D) Surface representations of the views for A and B, respectively.