Table 3.
12‐month weight change according to changes in mental health measures
| Change in mental health measures | Intensive lifestyle intervention (n = 30) | Metformin + standard care (n = 55) | ||
|---|---|---|---|---|
| n | Weight change, kg (95% CI)a | n | Weight change, kg (95% CI)a | |
| Improved or stable (I/S) | 13 | −6.9 (−9.4, −4.3) | 19 | −0.2 (−1.5, 1.2) |
| Worsened on any mental health measure (W) | 17 | −1.8 (−3.5, −0.1) | 36 | −0.1 (−1.5, 1.4) |
| Between group difference, P‐valueb | 30 | −5.1 (−2.3, −7.9), 0.001 | 57 | 0.1 (−2.1, 2.3), 0.919 |
| Worsened on 1 mental health measure | 10 | −3.0 (−4.8, −1.2) | 18 | −0.1 (−1.5, 1.3) |
| Worsened on 2 mental health measures | 2 | −0.4 (−16.9, 16.1) | 10 | −0.8 (−3.8, 2.2) |
| Worsened on 3 mental health measures | 5 | 0.3 (−5.1, 5.6) | 8 | 1.0 (−4.7, 6.6) |
a
A negative sign before the observed mean weight change or 95% CI indicates weight loss, and no sign indicates weight gain.
b
P‐value for the difference in weight loss between I/S and W groups was generated using the independent samples t‐test.