Table 3.
Shifts from baseline in patient‐reported Arizona Sexual Experiences Scale total score dysfunction categories at week 26
| Parameter | Usual care (N = 82) n (%) | NB + CLI (N = 71) n (%) |
|---|---|---|
| n a | 79 | 70 |
| Improved | 7 (8.9) | 14 (20.0) |
| From dysfunctional to not dysfunctional | 7 (8.9%) | 14 (20.0) |
| No change | 69 (87.3) | 50 (71.4) |
| Not dysfunctional at baseline and week 26 | 40 (50.6) | 40 (57.1) |
| Dysfunctional at baseline and week 26 | 29 (36.7) | 10 (14.3) |
| Worsened | 3 (3.8) | 6 (8.6) |
| From not dysfunctional to dysfunctional | 3 (3.8) | 6 (8.6) |
| P valueb | 0.0040 |
ASEX results were correlated with the presence of clinician‐diagnosed sexual dysfunction if one or more of the following criteria were met: (1) total score ≥19, (2) any individual score of ≥5 and (3) any three items with an individual score of ≥4. An assessment meeting one or more of these criteria was classified as ‘dysfunctional’.
ASEX, Arizona Sexual Experiences Scale; CLI, comprehensive lifestyle intervention; NB, sustained release combination of naltrexone and bupropion.
The number of participants with a score at both baseline and the week 26 visit. The percentages are calculated based on this n.
From a Cochran–Mantel–Haenszel test comparing shift frequencies for participants assigned to NB + CLI to those assigned to usual care, stratified by baseline BMI category.