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. 2018 Apr 11;7:64. doi: 10.1038/s41426-018-0065-6

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Maximum likelihood method was used to generate the phylogenetic tree. Bootstrap values were generated from 1000 replicates. Bootstrap values of more than 70 were indicated. The csep1 genes from C. concisus strains isolated from patients with active CD, active UC, remission CD and healthy controls were coloured in red, blue, orange and green, respectively. The csep1^P genes were underlined. *The csep1-6bpi gene