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The key residues identified through mutation experiments and predicted with present complex model.
| Key Residues in α6 | Key Residues in spacer | ||
|---|---|---|---|
| Identified | Predicted | Identified | Predicted |
| Asp1653 | Asp1653 | Leu591 | Leu591 |
| Asp1663 | — | Phe592 | Phe592 |
| — | Leu1657 | — | Arg636 |
| — | Ala1661 | — | Leu637 |
| — | Pro1662 | — | Pro638 |
| — | Leu1664 | Arg660 | — |
| — | Val1665 | Tyr661 | Tyr661 |
| Tyr665 | Tyr665 | ||
