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. 2018 Apr 4;9:320. doi: 10.3389/fphys.2018.00320

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Copyright © 2018 Kuk, Arnold, Wagner, Hecker, Sticht and Korff.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Morphometrical and functional analyses of superficial veins. Blood perfusion of one spider vein (left leg, knee level) was made from a healthy female volunteer using the PeriCam PSI blood perfusion imager (Superficial image: top panel; Perfusion measurement: bottom panel). An increase in blood perfusion of a spider vein was observed when the volunteer actively contract muscles of the leg (II) as opposed to the low perfusion level while standing still (I). Morphology and perfusion (upon muscle contraction) of the same spider vein was assessed 19.5 months later in a follow up recording (III).