Table 1.
Antimicrobial susceptibility of CR-ECL isolates with or without carbapenemase.
| Antimicrobial agents | Total (N = 138) |
Carbapenemase positive (N = 27) |
Carbapenemase negative (N = 111) |
P-value | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| R (%) | R | MIC50 | MIC90 | Range | R | MIC50 | MIC90 | Range | ||
| Ertapenem | 138 (100.0) | 27 (100.0) | 32 | 128 | 4–128 | 111 (100.0) | 8 | 32 | 2–64 | – |
| Imipenem | 31 (39.7) | 22 (81.5) | 8 | 32 | 0.25–128 | 9 (8.1) | 0.5 | 2 | 0.25–32 | < 0.001 |
| Meropenem | 31 (39.7) | 21 (77.8) | 16 | 128 | 0.5–128 | 10 (9.0) | 0.5 | 2 | 0.25–128 | < 0.001 |
| Ceftriaxone | 136 (98.6) | 27 (100.0) | 128 | 256 | 64–512 | 109 (98.2) | 64 | 128 | 1–512 | 0.482 |
| Ceftazidime | 134 (97.1) | 27 (100.0) | 128 | 512 | 64–512 | 107 (96.4) | 128 | 128 | 1–512 | 0.317 |
| Cefepime | 105 (76.1) | 27 (100.0) | 128 | 512 | 64–512 | 78 (70.3) | 64 | 256 | 1–512 | 0.001 |
| Ciprofloxacin | 74 (53.6) | 22 (81.5) | 8 | 32 | 0.25–32 | 52 (46.8) | 0.5 | 16 | 0.25–32 | 0.001 |
| Levofloxacin | 62 (44.9) | 20 (74.1) | 16 | 32 | 0.25–64 | 42 (37.8) | 4 | 32 | 0.25–128 | 0.001 |
| Gentamycin | 71 (51.4) | 24 (88.9) | 32 | 128 | 1–128 | 47 (42.3) | 1 | 32 | 1–256 | < 0.001 |
| Tobramycin | 73 (52.9) | 23 (85.2) | 32 | 128 | 1–256 | 50 (45.0) | 2 | 128 | 1–256 | < 0.001 |
| Colistin | 32 (23.2) | 7 (25.9) | 1 | 16 | 1–32 | 25 (22.5) | 1 | 8 | 1–32 | 0.707 |
| Tigecycline | 17 (12.3) | 4 (14.8) | 1 | 4 | 0.25–8 | 13 (11.7) | 0.5 | 2 | 0.25–8 | 0.660 |
Data are number resistant (% of resistance rates). P-value for comparisons of the resistance rates of carbapenemase-positive and carbapenemase-negative groups. Bold face indicates values that are significant (P < 0.05). R, resistance.