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. 2018 Apr 4;9:199. doi: 10.3389/fphar.2018.00199

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Copyright © 2018 Huang, Wang, Chen, Liu, Wang, Song, Zhang, Zhu, Huang, Liu, Song, Spencer and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chemical structure (A) and viability of N2a/WT cells (B) and N2a/APP cells (C) treated for 24 h with 0–25 μM Xn. N = 3. ^∗∗p < 0.01, ^∗∗∗∗p < 0.0001 compared with N2a/WT cells treated with vehicle. ^####p < 0.0001 compared with untreated N2a/APP cells.