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. 2018 Apr 4;9:621. doi: 10.3389/fimmu.2018.00621

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Copyright © 2018 Saito, Suzuki, Yoshimoto, Kaneko, Yamaoka, Shimizu, Mori, Okamoto, Kameyama, Amano, Tamaru, Tokuhira and Takeuchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes of lymphocyte numbers after MTX cessation in lymphoproliferative disorder (LPD) patients. Change in lymphocyte counts in regressive and persistent LPD compared with the range in the control group. Kruskal–Wallis test was used for comparing the three groups. ^†Regressive vs. control, P < 0.05; regressive vs. persistent, P < 0.05. *P < 0.05 for comparison with the value at week 0 in each group. MTX, methotrexate.