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. 2018 Apr 4;9:350. doi: 10.3389/fphys.2018.00350

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Copyright © 2018 Dib, Payen, Bourreau, Munier, Grimaud, Fajloun, Loufrani, Henrion and Fassot.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Blood pressure and morphometry of thoracic aorta at pre-hypertensive (3 months) and hypertensive (18 months) stages in control (CMO) and diabetic (DMO) mother offspring. (A) Evolution of systolic blood pressure (SBP). (B) Morphometric measurements of internal diameter and media to lumen ratio (M/L ratio) of CMO (open bars, n = 12 at 3 and 18 months of age) and DMO (solid bars, n = 13 at 3 months of age and n = 5 at 18 months of age) rats; each bar graph represents mean ± SEM. ^#p < 0.05 and ^###p < 0.001 18 months vs. 3 months of age, ^*p < 0.05 and ^***p < 0.001 DMO vs. CMO.