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. 2018 Apr 4;9:640. doi: 10.3389/fimmu.2018.00640

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Copyright © 2018 Nunes, Silva, Ampuero, Noronha, Souza, Correia, Khouri, Boaventura, Barral, Ramos, Brodskyn, Oliveira and Tavares.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Canonical pathways associated with innate immune response identified in localized cutaneous leishmaniasis (LCL). (A) p-Value of 13 canonical pathways common to both data sets, GSE55664 (purple) and GSE63931 (orange), and related to the innate immune response. Each symbol represents one pathway identified by numbers and listed on the right. The most significant pathways in GSE66554 (B) and GSE63931 (C) are identified by p-value and percentage of molecules that are targets for LCL microRNAs.