Figure 2.

Heatmap of experimentally validated union pathways of investigated group of miRNAs using miRPath Database (Vlachos et al., 2015). In union pathways the enrichment analysis is performed and significance levels (p-values) are calculated between each miRNA and every pathway. Then, for each pathway a merged p-value is extracted using Fisher's meta-analysis method, which signify if a particular pathway is targeted by at least one miRNA out of the initially selected group (Vlachos et al., 2015). Different colors of cells mean different level of significance [log (p-value) in Color Key].