Table 3.
List of validated target genes of investigated miRNAs according to Human MicroRNA Disease Database (Lu et al., 2008; Li et al., 2014).
| miRNA | Target genes | Diseases |
|---|---|---|
| miR-9 | ITGB1 | Breast cancer |
| JAK, CAMTA1 | Glioblastoma | |
| MMP14 | Neuroblastoma | |
| ETS1, NKFB1, CDX2, CCND1 | Gastric cancer | |
| miR-124a | IQGAP1 | Breast cancer |
| ROCK2, EZH2, PIK3CA | Hepatocellular carcinoma | |
| CDK4 | Glioma | |
| CDK6, HMGA1 | Medulloblastoma | |
| AR | Prostatic cancer | |
| miR-132 | TMEM106B | Dementia |
| miR-143 | GCK, MACC1, DNMT3A, KRAS | Colorectal cancer |
| ERK5 | B-cellular lymphoma, Obesity | |
| RAS | Pancreatic cancer | |
| PTGS2, SERPINE1, BCL2 | Uterine cervical neoplasm | |
| miR-206 | ESR1 | Breast cancer |
| Notch3 | Neoplasm | |
| MET | Rhabdomyosarcoma | |
| CCND2 | Gastric cancer | |
| miR-338 | SMO | Hepatocellular carcinoma |
| CCND1 | Hepatitis B | |
| miR-451a | IKBKB | Hepatocellular carcinoma |
| RAB14 | Non-small cell lung cancer | |
| YWHAZ | Diabetic nephropathy | |
| MDR, ABCB1 | Neoplasm | |
| miR-638 | / | |
| miR-663a | / | |
| let-7b | BCL2L1 | Hepatocellular carcinoma |
| KRAS | Non-small cell lung cancer | |
| IL13 | Inflammation | |
| ITGB3, CCND1 | Melanoma | |
| HMGA2, RAS | Neoplasm |