Figure 6.

Comparison of model results to in vitro infection data. Data points were extracted from Keum et al. (2012) and the lines were obtained by fitting the intracellular model to the data where we assumed the measured positive strands were the sum of the positive strands used for translation, R_t and in replication complexes, R_c. As before we fixed the export rate with ρ = 0.1 d⁻¹, τ = 0.5 d⁻¹, and k = 0.8 d⁻¹. The initial time t₀ = 0. Based on the data we set R_t0 = 12.8. Other parameters were estimated and were found to be α = 30 d⁻¹, μ_t = 24 d⁻¹, r = 3.18 d⁻¹, μ_c = 1.05 d⁻¹, R_max = 100 molecules, σ = 0.1 d⁻¹ and θ = 1.2 d⁻¹.