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. 2018 Apr 4;9:275. doi: 10.3389/fphar.2018.00275

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Copyright © 2018 Cheng, Liu, Lu, Yan, Huang, Meng and Li.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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miR-203 was down-regulated in EtOH-fed mice and EtOH-induced AML-12 cells. (A) Representative hematoxylin and eosin (H&E) staining of liver tissues (×400). (B) Body weights and the liver to body weight ratio after ethanol feeding. (C) Hepatic triglyceride (TG) and total cholesterol (TCH) levels. (D) Serum ALT and AST levels. (E) One-step qRT-PCR for miR-203 expression in EtOH-fed mice liver tissues compared to normal liver tissues and AML-12 cell line. (F) AML-12 cell line was treated with ethanol (0, 50, 75, 100, 150, 200) mM for 24 h the cell viability. ^∗p < 0.05, ^∗∗p < 0.01 versus control group.