Figure 6.

Absolute numbers of B-cell and B-cell subsets before (circles) and 2 weeks after (triangles) a first tetanus, diphtheria, and acellular pertussis booster vaccination in Dutch adults 25–29 years of age. Gating of populations (all SSC^low): B-cell: CD45⁺CD19⁺; translational: CD45⁺CD27⁻CD38⁺; plasmablast: CD45⁺CD27⁺CD38⁺; naïve mature: CD45⁺CD27⁻IgD⁺CD38^dim; natural effector: CD45⁺CD27⁺IgD⁺CD38^dim; CD27⁻ memory: CD45⁺CD27⁻IgD⁻CD38^dim; CD27⁺ memory: CD45⁺CD27⁺IgD⁻CD38^dim. Note, black solid line represents the geometric mean numbers with corresponding 95% confidence intervals, *p-value <0.05.