Table 1.
Testing of the Association Between Prenatal Schistosoma haematobium or Filarial Exposure and the 2 Principal Components (PC1 and PC2) of the 6–30-Month Trajectories of Early Life Antivaccine Immunoglobulin G Responses
| Exposure, Outcome, PC | Estimate (95% CI) | P a |
|---|---|---|
| Schistosomiasis | ||
| H. influenzae | ||
| PC1 | 0.372 (−.88 to 1.63) | .5529 |
| PC2 | 0.776 (−.15 to 1.70) | .0945 |
| Tetanus toxoid | ||
| PC1 | −0.765 (−1.89 to .35) | .1718 |
| PC2 | −0.629 (−1.34 to .08) | .0781 |
| Hepatitis B virus | ||
| PC1 | 0.002 (−1.06 to 1.07) | .9965 |
| PC2 | 0.248 (−.28 to .78) | .3478 |
| Diphtheria toxoid | ||
| PC1 | −1.2 (−2.42 to .02) | .0485 |
| PC2 | 0.528 (−.22 to 1.27) | .1571 |
| Filariasis | ||
| H. influenzae | ||
| PC1 | −0.136 (−1.65 to 1.38) | .8574 |
| PC2 | 1.228 (.13 to 2.32) | .0251 |
| Tetanus toxoid | ||
| PC1 | −0.596 (−1.95 to .76) | .3799 |
| PC2 | −0.546 (−1.36 to .27) | .1819 |
| Hepatitis B virus | ||
| PC1 | −1.387 (−2.71 to −.06) | .0363 |
| PC2 | 0.389 (−.26 to 1.04) | .2339 |
| Diphtheria toxoid | ||
| PC1 | −3.597 (−5.00 to −2.19) | 3.1 × 10–7 |
| PC2 | 0.617 (−.24 to 1.47) | .1499 |
See Methods for a description of the PC analyses.
Abbreviations: CI, confidence interval; Hib, Haemophilus influenzae b.
aValues <.05 are considered statistically significant.