TABLE 3.
Summary of Independent Mutations in the Liver cII Gene From Rats Fed 2% and 8% Comfrey Roots
| Types of mutation | Control
|
2% Comfrey a
|
8% Comfrey b
|
|||
|---|---|---|---|---|---|---|
| Number | % | Number | % | Number | % | |
| Transitions | ||||||
| G:C → A:T | 20 | 43 | 24 | 12 | 11 | 11 |
| A:T → G:C | 1 | 2 | 9 | 4 | 6 | 6 |
| Transversions | ||||||
| G:C → T:A | 9 | 20 | 83 | 42 | 40 | 41 |
| G:C → C:G | 5 | 11 | 11 | 6 | 6 | 6 |
| A:T → T:A | 1 | 2 | 5 | 2 | 4 | 4 |
| A:T → C:G | 3 | 7 | 7 | 3 | 4 | 4 |
| Frameshifts | 7 | 15 | 26 | 13 | 14 | 14 |
| Complex | 0 | 0 | 2 | 1 | 1 | 1 |
| Tandem-base substitution | 0 | 0 | 33 | 17 | 13 | 13 |
| Total mutants screened | 46 | 200 | 99 | |||
a
Data from Mei et al. (2005).
b
Data from Mei et al. (2006).