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. Author manuscript; available in PMC: 2018 Apr 11.
Published in final edited form as: Ann Vasc Surg. 2017 Oct 26;46:193–204. doi: 10.1016/j.avsg.2017.10.001

Fig. 4.

Fig. 4

Angiotensin II stimulation has no effect on IL-6 and MCP-1 mRNA expression. (A) IL-6 and (B) MCP-1 mRNA expression, in aortic tissue held at optimal (1.2 g, n = 7) tension in a solution void or containing 100 nM angiotensin II (AngII, n = 4). (C) IL-6 and (D) MCP-1 mRNA expression in VSMCs held under static conditions in media void or containing 100 nM AngII or AngII and 2.5 µM WP1066. (E) IL-6 and (F) MCP-1 mRNA expression in VSMCs held under tension (12% biaxial cyclic stretch) conditions in media void or containing 100 nM AngII or AngII and 2.5 µM WP1066. *P < 0.05 versus static; #P < 0.05 versus tension.