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. 2018 Apr 10;7:8. doi: 10.1186/s40164-018-0100-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — PRL-3 was expressed in cHL biopsies. a PRL-3 expression in HRS cells (arrows) and not in the surrounding cells measured by IHC. Dashed arrow indicates a so-called “mummy” cell. b IHC with negative PRL-3 expression in HRS cells (indicated by arrows). c, d PRL-3 expression did not correlate to clinical endpoints like stage (c) or survival (d). Analysis of gene expression data from Steidl et al. [22]. Line in the middle of the box represent median and boxes represent 25–75 percentiles of log2 median-centered intensity of PRL-3 expression. Whiskers represent minimum and maximum values

(Data adapted from http://www.oncomine.org)