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. 2018 Apr 10;16:91. doi: 10.1186/s12967-018-1470-2

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Correlations of urinary miR-196a levels with clinical outcome. a Urinary miR-196a concentrations were significantly higher in patients who would develop ESRD as compared with those who would not. b In patients with nephrotic-range proteinuria, urinary miR-196a levels were also significantly higher in patients who would develop ESRD as compared with those who would not. Urinary miR-196a was significantly correlated with proteinuria (c) and eGFR (d). Bars indicate median with inter-quartile range. ESRD end-stage renal disease, non-ESRD not progression to ESRD, NS nephrotic-range proteinuria, eGFR estimated glomerular filtration rate