Table 1.
Baseline characteristics of patients with IgG4-RD (n = 215)
| Variable | Value |
|---|---|
| Sex (male:female) | 2.2:1 |
| Age (years) | 54 (46, 62) |
| Diagnosis, n (%) | |
| Definite | 102 (47.4%) |
| Probable | 10 (4.7%) |
| Possible | 103 (47.9%) |
| Disease duration (months) | 12 (4, 36) |
| IgG4-RD RI | 14 (10, 18) |
| Allergy history, n (%) | 115 (53.5%) |
| Number of organs involved, n (%) | |
| 1 ~ 2 | 78 (36.3%) |
| 3 ~ 4 | 101 (47.0%) |
| ≥ 5 | 36 (16.7%) |
| Organ involvement, n (%) | |
| Mikulicz’s disease | 138 (64.2%) |
| Dacryoadenitis | 95 (44.2%) |
| Sialoadenitis | 124 (57.7%) |
| Autoimmune pancreatitis | 91 (42.3%) |
| Sclerosing cholangitis | 58 (27.0%) |
| Retroperitoneal fibrosis | 50 (23.3%) |
| Lung disease | 62 (28.8%) |
| Kidney involvement | 19 (8.8%) |
| Lymphadenopathy | 139 (64.7%) |
| Sinusitis | 62 (28.8%) |
| Prostatitis | 30 (14.0%) |
| Skin involvement | 12 (5.6%) |
| Aortitis/periaortitis | 12 (5.6%) |
| Ophthalmic disease (except for dacryoadenitis) | 7 (3.3%) |
| Mediastinal fibrosis | 9 (4.2%) |
| Hepatopathy | 6 (2.8%) |
| Thyroiditis | 2 (0.9%) |
| Central nervous system involvement | 2 (0.9%) |
| Laboratory tests at baseline | |
| Eosinophils (%) | 3.2 (1.6, 6.3) |
| ESR (mm/h) | 25 (10, 59.5) |
| CRP (mg/L) | 3.78 (1.15, 10.81) |
| IgG (g/L) | 18.87 (15.13, 24.53) |
| IgG4 (mg/L) | 8960 (3500, 18,600) |
| IgE (kU/L) | 362.5 (132.5, 774) |
All the continuous non-normally distributed data are presented as median (first quartile, third quartile)
IgG4-RD IgG4-related disease, RI responder index, ESR erythrocyte sedimentation rate, CRP hyper-sensitivity C-reactive protein