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. 2018 Apr 10;16:76. doi: 10.1186/s12957-018-1378-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 11 — The expression of four hub genes was decreased in TCGA LUSC samples and ROC curve analysis. a The expression of EPAS1 in 502 LUSC and 49 non-cancerous lung tissues. b ROC curve was generated to assess the diagnostic ability of EPAS1 in 502 LUSC and 49 non-cancerous lung tissues. The AUC was 0.929 (95% CI 0.9023 to 0.9558, p < 0.001). c The expression of PRKCE in 502 LUSC and 49 non-cancerous lung tissues. d The ROC curve was generated to assess the diagnostic ability of PRKCE in 502 LUSC and 49 non-cancerous lung tissues. The AUC was 0.996 (95% CI 0.9929 to 0.9995, p < 0.001). e The expression of NR3C1 in 502 LUSC and 49 non-cancerous lung tissues. f The ROC curve was generated to assess the diagnostic ability of NR3C1 in 502 LUSC and 49 non-cancerous lung tissues. The AUC was 0.958 (95% CI 0.9404 to 0.9749, p < 0.001). g The expression of RHOB in 502 LUSC and 49 non-cancerous lung tissues. h The ROC curve was generated to assess the diagnostic ability of RHOB in 502 LUSC and 49 non-cancerous lung tissues. The AUC was 0.929 (95% CI 0.9238 to 0.9774, p < 0.001)