Table 2.

Clinicopathological parameters and miR-182 expression in LUSC data from TCGA database

Characteristic		n	Relevant expression of miR-182 (log2x)
			Mean ± SD	t/F value	p value
Tissue	LUSC	338	14.4295 ± 1.16110	− 18.590a	< 0.001
	Non-cancerous	45	12.2828 ± 0.64852
Gender	Male	254	14.4792 ± 1.14885	1.371	0.171
	Female	84	14.2791 ± 1.19174
Age (years)	≤ 60	177	14.4281 ± 1.13491	− 0.023	0.982
	> 60	161	14.4310 ± 1.19279
Pathologic T	T1	80	14.4445 ± 1.13309	0.912b	0.435
	T2	189	14.4866 ± 1.16154
	T3	58	14.3072 ± 1.22759
	T4	11	13.9834 ± 0.98341
T	T1 + T2	269	14.4741 ± 1.15120	1.396	0.164
	T3 + T4	69	14.2556 ± 1.19150
Nodes	No	217	14.4176 ± 1.15198	− 0.250	0.803
	Yes	121	14.4507 ± 1.18181
Metastasis	No	259	14.4528 ± 1.18483	0.669	0.504
	Yes	79	14.3529 ± 1.08334
Pathologic stage	I	157	14.3819 ± 1.16704	0.654b	0.581
	II	125	14.4825 ± 1.20539
	III	50	14.4849 ± 1.05204
	IV	3	13.6550 ± 0.94917
Stage	I-II	282	14.4265 ± 1.18313	− 0.065	0.948
	III-IV	53	14.4379 ± 1.05597
Anatomic organ subdivision	L_lower	41	14.3997 ± 1.31582	0.795b	0.529
	L_upper	90	14.2951 ± 1.00576
	R_lower	76	14.5891 ± 1.17043
	R_middle	11	14.6375 ± 1.30430
	R_upper	96	14.4124 ± 1.12167
Tumor location	Peripheral	73	14.3940 ± 1.12931	0.288	0.774
	Central	107	14.3435 ± 1.17386

Statistically significant results (p < 0.05) are indicated in bold

LUSC lung squamous cell carcinoma, SD standard deviation

^aStudent’s t test was used for comparison between the experimental and control groups

^bOne-way analysis of variance (ANOVA) was used for the analysis of five groups