Table 1.

Dosing schema

Dose level	Rituximab: cycles 1-6, day 1, mg/m2	Ibrutinib: days 1-28 until progression/intolerance, mg/d	Lenalidomide: cycles 1-12, days 1-21/28, mg/d
Level −2	375	280	2.5
Level −1	375	420	2.5
Level 1*	375	420	5
Level 2	375	420	10
Level 3	375	420	15

^*Dose level 1 is the starting dose level.