Skip to main content
. 2018 Apr;58(4):510–518. doi: 10.1165/rcmb.2017-0230OC

Table 2.

The Top 25 Differentially Expressed Genes between Pulmonary Nontuberculous Mycobacterial Cases and Control Subjects

Rank Gene Name Entrez ID Fold Change d-Statistic Name
1 FLJ45825 100505530 1.657 2.646 Uncharacterized LOC100505530
2 GZMK 3003 1.61 2.857 Granzyme K (granzyme 3; tryptase II)
3 TARP 445347 1.609 2.619 TCR γ alternate reading frame protein
4 TARP 445347 1.609 2.619 TCR γ alternate reading frame protein
5 XCL2 6846 1.553 3.269 Chemokine (C motif) ligand 2
6 A2M 2 1.507 2.293 α-2-macroglobulin
7 CRTAM 56253 1.465 3.57 Cytotoxic and regulatory T cell molecule
8 PMS2P1 5379 1.453 4.053 Postmeiotic segregation increased 2 pseudogene 1
9 FCRL3 115352 1.446 3.26 Fc receptor-like 3
10 PZP 5858 1.435 2.275 Pregnancy-zone protein
11 TIGIT 201633 1.4 3.333 T cell immunoreceptor with Ig and ITIM domains
12 PPIH 10465 1.393 2.897 Peptidylprolyl isomerase H (cyclophilin H)
13 AK5 26289 1.39 2.515 Adenylate kinase 5
14 MUC12 10071 1.39 2.388 Mucin 12, cell surface associated
15 IFNG 3458 1.382 2.622 IFN, γ
16 FAHD2A 51011 1.364 3.021 Fumarylacetoacetate hydrolase domain containing 2A
17 SMA4 11039 1.361 3.602 Glucuronidase, β pseudogene
18 VSIG1 340547 1.356 2.784 V-set and immunoglobulin domain containing 1
19 SAMD3 154075 1.35 2.367 Sterile α motif domain containing 3
20 XCL1 6375 1.348 2.247 Chemokine (C motif) ligand 1
21 IL2RB 3560 1.347 2.242 IL-2 receptor, β
22 PSPH 5723 1.339 2.232 Phosphoserine phosphatase
23 LDHB 3945 1.336 2.312 Lactate dehydrogenase B
24 NELL2 4753 1.323 2.276 NEL-like 2 (chicken)
25 NFATC2 4773 1.322 2.804 Nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 2

Definition of abbreviations: ITIM = immunoreceptor tyrosine-based inhibition motif; TCR = T-cell receptor.

Genes are ranked by fold change; all displayed decreased expression in pulmonary nontuberculous mycobacterial cases.