Table 2.
The Top 25 Differentially Expressed Genes between Pulmonary Nontuberculous Mycobacterial Cases and Control Subjects
Rank | Gene Name | Entrez ID | Fold Change | d-Statistic | Name |
---|---|---|---|---|---|
1 | FLJ45825 | 100505530 | 1.657 | 2.646 | Uncharacterized LOC100505530 |
2 | GZMK | 3003 | 1.61 | 2.857 | Granzyme K (granzyme 3; tryptase II) |
3 | TARP | 445347 | 1.609 | 2.619 | TCR γ alternate reading frame protein |
4 | TARP | 445347 | 1.609 | 2.619 | TCR γ alternate reading frame protein |
5 | XCL2 | 6846 | 1.553 | 3.269 | Chemokine (C motif) ligand 2 |
6 | A2M | 2 | 1.507 | 2.293 | α-2-macroglobulin |
7 | CRTAM | 56253 | 1.465 | 3.57 | Cytotoxic and regulatory T cell molecule |
8 | PMS2P1 | 5379 | 1.453 | 4.053 | Postmeiotic segregation increased 2 pseudogene 1 |
9 | FCRL3 | 115352 | 1.446 | 3.26 | Fc receptor-like 3 |
10 | PZP | 5858 | 1.435 | 2.275 | Pregnancy-zone protein |
11 | TIGIT | 201633 | 1.4 | 3.333 | T cell immunoreceptor with Ig and ITIM domains |
12 | PPIH | 10465 | 1.393 | 2.897 | Peptidylprolyl isomerase H (cyclophilin H) |
13 | AK5 | 26289 | 1.39 | 2.515 | Adenylate kinase 5 |
14 | MUC12 | 10071 | 1.39 | 2.388 | Mucin 12, cell surface associated |
15 | IFNG | 3458 | 1.382 | 2.622 | IFN, γ |
16 | FAHD2A | 51011 | 1.364 | 3.021 | Fumarylacetoacetate hydrolase domain containing 2A |
17 | SMA4 | 11039 | 1.361 | 3.602 | Glucuronidase, β pseudogene |
18 | VSIG1 | 340547 | 1.356 | 2.784 | V-set and immunoglobulin domain containing 1 |
19 | SAMD3 | 154075 | 1.35 | 2.367 | Sterile α motif domain containing 3 |
20 | XCL1 | 6375 | 1.348 | 2.247 | Chemokine (C motif) ligand 1 |
21 | IL2RB | 3560 | 1.347 | 2.242 | IL-2 receptor, β |
22 | PSPH | 5723 | 1.339 | 2.232 | Phosphoserine phosphatase |
23 | LDHB | 3945 | 1.336 | 2.312 | Lactate dehydrogenase B |
24 | NELL2 | 4753 | 1.323 | 2.276 | NEL-like 2 (chicken) |
25 | NFATC2 | 4773 | 1.322 | 2.804 | Nuclear factor of activated T cells, cytoplasmic, calcineurin-dependent 2 |
Definition of abbreviations: ITIM = immunoreceptor tyrosine-based inhibition motif; TCR = T-cell receptor.
Genes are ranked by fold change; all displayed decreased expression in pulmonary nontuberculous mycobacterial cases.