Table 3.

Multivariate Models of the Relationship between Forced Expiratory Volume in 1 Second % of Predicted and Neutrophil and Lymphocyte Quantifications

	Neutrophil Count	Neutrophil %	Lymphocyte Count	Lymphocyte %	Current Smoking	Neutrophil Count × Current Smoking	Neutrophil % × Current Smoking	Lymphocyte Count × Current Smoking	Lymphocyte % × Current Smoking	Adjusted R2
Cell proportions	—	0.39 (0.10)*	—	0.75 (0.11)*	—	—	—	—	—	0.274
Cell counts	−2.19 (0.20)*	—	1.72 (0.44)*	—	—	—	—	—	—	0.275
Cell counts + current smoking	−2.73 (0.27)*	—	1.79 (0.58)*	—	−5.74 (2.48)*	1.21 (0.40)*	—	−0.06 (0.90)	—	0.276
Cell proportions + counts + current smoking	−2.47 (0.62)*	0.74 (0.14)*	−0.41 (1.32)	0.94 (0.16)*	−10.99 (18.91)	0.24 (1.03)	0.13 (0.23)	1.85 (2.07)	−0.1 (0.27)	0.285

Adjusted R2 is the variance explained adjusted for model complexity. Cell counts are in units of 1,000 cells/μl. Each row corresponds to a separate multivariate model. Each model is also adjusted for oral and inhaled steroid use.

^*P < 0.05.