Table 3.

Association between anxiety symptoms and dementia in the oldest old women

Logistic regression	Anxiety symptoms	Unadjusted		Multivariable-adjusted*
		Odds ratio (95% confidence interval)	p-value	Odds ratio (95% confidence interval)	p-value
Model 1	Any	†1.47 (1.10–1.97)	0.009	†1.56 (1.07–2.26)	0.020
	None	1.00 (reference)
Model 2	Moderate/ severe	1.27 (0.82–1.96)	0.289	1.27 (0.71–2.28)	0.425
	Mild	†1.58 (1.14–2.18)	0.005	†1.66 (1.12–2.45)	0.012
	None	1.00 (reference)
Model 3	Incident	†1.85 (1.01–3.39)	0.045	1.54 (0.74–3.20)	0.247
	Persistent	1.08 (0.58–2.03)	0.809	0.83 (0.34–2.03)	0.690
	Receded	†2.81 (1.17–6.74)	0.021	†3.80 (1.22–11.87)	0.021
	Never	1.00 (reference)

^*Models are adjusted for demographics (age, education and marital status), health behaviors (smoking, alcohol use and exercise), medical history (hypertension, myocardial infarction, stroke, and diabetes), psychotropic medications (benzodiazepine, non-benzodiazepine non-barbiturate sedative hypnotic and antidepressant), depression and poor sleep

^**Reference group: normal cognition

^†p<0.05