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. 2018 Mar 20;19(1):20–34. doi: 10.7181/acfs.2018.19.1.20

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Copyright © 2018 The Korean Cleft Palate-Craniofacial Association

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 5. — Histological findings of the wound (Masson’s trichrome stain, ×40). On day 10, (A) the Oncorhynchus mykiss-derived polydeoxyribonucleotide (PDRN) injection group, (B) the Oncorhynchus keta-derived PDRN injection group, (C) the O. keta-derived PDRN cream group, (D) the normal saline soaked dressing group. Asterisks (*) indicate areas of granulation tissue proliferation. Collagen is the blue-colored cells in the area where the granulation tissue is proliferated. At all time points (days 4, 7, and 10), pronounced collagen formation was observed in the PDRNbased treatment groups in comparison with that in the normal saline soaked group.