Figure 1.

SPHK1 expression was upregulated in breast cancer tissue samples. (A) RT-PCR assay was used to detect the SphK1 expression in human breast cancer tissue samples and the paired adjacent normal breast tissues. Two-tailed Student t-test was used for statistical significance. Each dot represents an individual patient. (B) The mRNA expression of SphK1 in different breast cancer subtypes. (C) The mRNA expression of SphK1 in triple negative breast cancer (TNBC) and non-TNBC. (D) Kaplan-Meier plots of overall survival (OS) in all breast cancer patients. (E) Kaplan-Meier plots of progression-free survival (PFS) in all breast cancer patients.