Figure 4.
Extraction of significant modules and VennPlex representation of differentially expressed genes (DEGs).
Notes: (A) A significant module enriched by upregulated genes in primitive neuroectodermal tumor (PNET) vs fetal brain. White nodes represent upregulated genes. (B) A significant module enriched by downregulated genes in PNET vs fetal brain. Gray nodes stand for the downregulated genes. (C) A significant module enriched by downregulated genes in PNET vs adult brain. Gray nodes stand for the downregulated genes. (D) A significant module enriched by upregulated genes in PNET vs adult brain. White nodes represent upregulated genes. (E) VennPlex representation of DEGs in PNET vs fetal brain and PNET vs adult brain. The VennPlex numerical set description is shown in the lower right corner, which indicates the number of factors in each intersection that are upregulated (italic), downregulated (underlined), or contraregulated (gray).