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AA-PMe inhibits HUVEC viability. HUVECs were treated with DMSO vehicle or varying concentrations (5, 10, or 25 μM) of (A) AA or (B) AA-PMe for 24, 48, and 72 hours. Both adherent and non-adherent cells were collected and processed for determination of viable cell number. Mean values ± SEM are shown, n=3. *P<0.05.
Abbreviations: AA, asiatic acid; AA-PMe, N-(2α,3β,23-acetoxyurs-12-en-28-oyl)-L-proline methyl ester; HUVEC, human umbilical vein endothelial cell; DMSO, dimethyl sulfoxide.
