Table 3.
Predictors for clinical outcome in stable CAD and ACS patients
| Stable CAD
|
ACS
|
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Composite outcome | ||||||
| CHADS2a | 2.6671 | 2.1660–3.2843 | <0.0001 | 2.1593 | 1.9830–2.3513 | <0.0001 |
| R CHADS2b | 2.0443 | 1.7664–2.3660 | <0.0001 | 1.9184 | 1.8178–2.0246 | <0.0001 |
| All-cause death | ||||||
| CHADS2a | 1.6533 | 1.1768–2.3228 | 0.0037 | 1.5993 | 1.4150–1.8077 | <0.0001 |
| R2CHADS2b | 1.5429 | 1.2284–1.9379 | <0.0001 | 1.6741 | 1.5519–1.8059 | <0.0001 |
| Cardiovascular death | ||||||
| CHADS2a | 1.5574 | 1.3347–1.8173 | <0.0001 | 1.5483 | 1.1757–3.0364 | 0.0086 |
| R2CHADS2b | 1.6492 | 1.4981–1.8156 | <0.0001 | 1.6282 | 1.4856–1.7846 | <0.0001 |
Notes: Cox regression multivariate:
model 1 was adjusted for sex, smoking, BMI, hyperlipidemia, GFR, TC, TG, LDL-C, HDL-C, and medication at discharge, while
model 2 was adjusted for the aforementioned covariates except GFR. CHADS2, congestive heart failure, hypertension, age, diabetes, and stroke/transient ischemic attack; R2CHADS2, renal dysfunction, congestive heart failure, hypertension, age, diabetes, and stroke/transient ischemic attack.
Abbreviations: ACS, acute coronary syndrome; BMI, body mass index; CAD, coronary artery disease; GFR, glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides.