Table 2.
Biochemical parameters of blood serum
| ALT (mmol/L) | AST (mmol/L) | CRE (mmol/L) | BUN (mmol/L) | |
|---|---|---|---|---|
| WT | 83.77±7.73 | 33.07±15.12 | 178.22±14.15 | 7.18±0.42 |
| TNFα-Tg + PBS | 69.91±20.97 | 31.64±12.52 | 165.83±23.76 | 7.54±0.72 |
| TNFα-Tg + PA | 66.54±10.08 | 37.72±20.11 | 179.57±19.44 | 7.39±1.06 |
| TNFα-Tg + TP | 170.87±15.32*,# | 160.17±14.68*,# | 343.70±49.90*,# | 13.32±2.17*,# |
| TNFα-Tg + PAT | 81.58±14.12 | 38.58±18.38 | 175.36±35.76 | 7.84±1.30 |
Notes:
#
P<0.05, vs TNFα-Tg + PBS.
*
P<0.05, vs WT.
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; CRE, creatinine; BUN, blood urea nitrogen; WT, wild-type; TNFα-Tg, tumor necrosis factor α transgenic; PBS, phosphate buffer saline; PA, poly-γ-glutamic acid-grafted di-tert-butyl L-aspartate hydrochloride; TP, triptolide; PAT, TP-loaded poly-γ-glutamic acid-grafted di-tert-butyl L-aspartate hydrochloride.