Table 2.
Functional and pathway enrichment analysis of upregulated genes in HCC
| Term | Description | Count | P-value |
|---|---|---|---|
| GO: 0055114 | Oxidation–reduction process | 17 | 3.8E-8 |
| GO: 0020037 | Heme binding | 8 | 4.2E-6 |
| GO: 0005634 | Nucleus | 8 | 1.0E0 |
| GO: 0031090 | Organelle membrane | 7 | 3.9E-6 |
| GO: 0005506 | Iron ion binding | 7 | 9.3E-5 |
| GO: 0005789 | Endoplasmic reticulum membrane | 7 | 2.4E-1 |
| GO: 0004497 | Monooxygenase activity | 6 | 8.4E-6 |
| KEGG: hsa05204 | Chemical carcinogenesis | 4 | 1.8E-2 |
| KEGG: hsa00982 | Drug metabolism-cytochrome P450 | 3 | 8.1E-2 |
| KEGG: hsa00380 | Tryptophan metabolism | 6 | 7.2E-6 |
| KEGG: hsa00830 | Retinol metabolism | 5 | 1.0E-3 |
Abbreviations: GO, gene ontology; HCC, hepatocellular carcinoma; KEGG, Kyoto Encyclopedia of Genes and Genomes.