Table 4.
Summary of blood biochemical analysis in rats fed corn silk extract in subacute toxicity study
| Parameter | Dose of corn silk extract (mg/kg body weight) | |||
|---|---|---|---|---|
|
| ||||
| 0 (control) | 5 | 50 | 500 | |
| AST (IU/L) | 75.0±9.01) | 71.0±12.0 | 62.0±12.0 | 61.0±21.0 |
| ALT (IU/L) | 32.0±16.0 | 40.0±8.0 | 32.0±10.0 | 29.0±4.0 |
| ALP (IU/L) | 257.0±23.0 | 299.0±82.0 | 255.0±54.0 | 242.0±48.0 |
| BUN (mg/dL) | 15.0±7.0 | 21.0±4.0 | 17.0±1.0 | 18.0±2.0 |
| CRE (mg/dL) | 0.3±0.1 | 0.3±0.1 | 0.3±0.0 | 0.3±0.0 |
| CPK (IU/L) | 236.0±206.0 | 78.0±33.0 | 63.0±15.0 | 66.0±59.0 |
| GLU (mg/dL) | 205.0±37.0 | 228.0±31.0 | 210.0±14.0 | 183.0±65.0 |
| TP (g/dL) | 6.3±0.5 | 6.4±0.3 | 6.3±0.1 | 5.9±0.4 |
| ALB (g/dL) | 2.0±0.2 | 2.1±0.1 | 2.0±0.1 | 1.9±0.1 |
| A/G (ratio) | 0.48±0.02 | 0.47±0.02 | 0.48±0.02 | 0.47±0.02 |
| CHO (mg/dL) | 130.0±18.0 | 151.0±17.0 | 153.0±9.0 | 140.0±18.0 |
| TG (mg/dL) | 93.0±24.0 | 69.0±17.0 | 79.0±23.0 | 74.0±9.0 |
| IP (mg/dL) | 9.93±0.91 | 9.64±0.87 | 10.04±1.57 | 9.04±0.95 |
| Ca (mg/dL) | 9.9±0.6 | 10.2±0.6 | 9.8±0.3 | 9.6±0.4 |
| Na (mmol/L) | 148.0±1.0 | 146.0±1.0 | 149.0±1.0 | 149.0±1.0 |
| K (mmol/L) | 7.2±0.4 | 7.1±0.1 | 7.0±1.2 | 6.1±0.7 |
| Cl (mmol/L) | 117.0±1.0 | 115.0±2.0 | 118.0±1.0 | 117.0±1.0 |
1)
Data are presented as mean±SD (n=5 in each group, P>0.05 for all comparisons between corn silk extract treated groups and the control group).
AST, aspartate aminotransferase; ALT, alanine aminotransferase; ALP, alkaline phosphatase; BUN, blood urea nitrogen; CRE, creatinine; CPK, creatine phosphokinase; GLU, glucose; TP, total protein; ALB, albumin; A/G, albumin/globulin ratio; CHO, total cholesterol; TG, triglyceride; IP, inorganic phosphorus.