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Buprenorphine Blocks CFA-induced Hyperalgesia in Response to Mechanical Stimuli of 60 g over the TMJ
| CFA | CFA + BUP | P | |
|---|---|---|---|
| Basal | 0.7 ± 0.4 | 1.3 ± 0.8 | .334 |
| D1 | 3.7 ± 0.5 | 0 ± 0 | .017 |
| D2 | 4.0 ± 0.6 | 0 ± 0 | .016 |
Data are presented as the mean number of nocifensive responses ± SEM out of five stimulations, n ≥ 3 for all conditions. SEM, standard error of the mean; CFA, complete Freund’s adjuvant; BUP, buprenorphine.
