Table 2.
First and second measurements in IFN-γ, TNF-α, cytokine levels, their mean values, standard deviation, mean lower and upper bound (95% confidence interval) and their statistical correlation with patient response.
| Mean (pg/ml) | Standard deviation (pg/ml) | Standard error (pg/ml) | 95% confidence interval for mean (pg/ml) |
p value (correlation with response) |
||
|---|---|---|---|---|---|---|
| Lower bound | Upper bound | |||||
| IFN-γ 1st | 1.23 | 0.430 | 0.084 | 1.06 | 1.40 | 0.195 |
| IFN-γ 2nd | 12.38 | 23.257 | 4.561 | 2.99 | 21.78 | 0.000 |
| TNF-α 1st | 1.215 | 0.3663 | 0.0718 | 1.067 | 1.363 | 0.275 |
| TNF-α 2nd | 1.638 | 1.0632 | 0.2085 | 1.209 | 2.068 | 0.12 |
| IL-1β 1st | 1.462 | 0.6469 | 0.1269 | 1.200 | 1.723 | 0.265 |
| IL-1β 2nd | 1.615 | 1.3587 | 0.2665 | 1.067 | 2.164 | 0.087 |
| IL-2 1st | 1.231 | 0.4297 | 0.0843 | 1.057 | 1.404 | 0.193 |
| IL-2 2nd | 1.846 | 1.1897 | 0.2333 | 1.366 | 2.327 | 0.017 |
| IL-4 1st | 2.3846 | 2.48317 | 0.48699 | 1.3816 | 3.3876 | 0.029 |
| IL-4 2nd | 4.7692 | 9.04348 | 1.77357 | 1.1165 | 8.4220 | 0.04 |
| IL-5 1st | 1.3846 | 0.63730 | 0.12499 | 1.1272 | 1.6420 | 0.379 |
| IL-5 2nd | 1.0769 | 0.27175 | 0.05329 | 0.9672 | 1.1867 | 0.193 |
| IL-6 1st | 32.5385 | 33.03239 | 6.47818 | 19.1964 | 45.8805 | 0.084 |
| IL-6 2nd | 27.8462 | 33.46364 | 6.56276 | 14.3299 | 41.3624 | 0.401 |
| IL-8 1st | 2.9231 | 3.65429 | 0.71667 | 1.4471 | 4.3991 | 0.066 |
| IL-8 2nd | 67.6923 | 204.34183 | 40.07473 | −14.8431 | 150.2278 | 0.009 |
| IL-10 1st | 2.3077 | 2.05464 | 0.40295 | 1.4778 | 3.1376 | 0.058 |
| IL-10 2nd | 2.9615 | 1.85969 | 0.36472 | 2.2104 | 3.7127 | 0.495 |
| IL-12 1st | 1.2000 | 0.33466 | 0.06563 | 1.0648 | 1.3352 | 0.093 |
| IL-12 2nd | 1.2769 | 0.37556 | 0.07365 | 1.1252 | 1.4286 | 0.726 |
IFN, interferon; IL, interleukin; TNF, tumor necrosis factor.