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Forkhead box M1 (FOXM1) acts as a direct target downstream of miR-212 in HCC. A, Schematic diagram of the presumed binding site of miR-212 and on the 3′-UTR of FOXM1 (WT, wild-type; Mut, mutant). B, The expression of miR-212 and FOXM1 in HCC specimens. Bar = 100 μm. n = 20, **P < .01. C, The results of luciferase reporter assay. n = 3, ** P < .01. D, Representative images of Western blot. HCC indicates hepatocellular carcinoma.
