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Gut microbial composition and diversity differ based on housing conditions, but are not significantly influenced by genotype. (A,D) Principal coordinates analysis of stool and ileal microbial composition of wild-type (WT) and Irgm1−/− (KO) mice in conventional (CV) and specific pathogen-free (SPF) conditions based on Bray–Curtis dissimilarity statistic. Richness measured using observed OTUs (B,E), and Chao1 index (C,F). n=11 CV WT, 11 CV KO, 7 SPF WT, 10 SPF KO. *FDR=0.024.
