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. 2018 Apr 11;13(4):e0195657. doi: 10.1371/journal.pone.0195657

Fig 3. CX3CR1 DNA vaccination reduced plaque formation in brachiocephalic arteries and aortic arch of atherosclerotic ApoE-/- mice.

Fig 3

(A) Representative images of atherosclerotic lesions from brachiocephalic arteries with Haemotoxylin & Eosin staining. (B) Quantitative analysis showing that there were significant reductions in plaque size (area of plaque/Lumen) in brachiocephalic arteries of both DEC-CX3CR1 vaccinated mice and Con-CX3CR1 vaccinated mice in comparison to adjuvant only and non-vaccinated control mice (*** p< 0.001;*p<0.05 respectively). (C) Quantitative analysis showing that there were significant reductions in plaque size (area of plaque/vessel) in brachiocephalic arteries of DEC-CX3CR1 vaccinated mice in comparison to adjuvant only and non-vaccinated control (**p< 0.01;*p<0.05 respectively).