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. Author manuscript; available in PMC: 2018 May 1.
Published in final edited form as: Virology. 2017 Mar 6;505:193–209. doi: 10.1016/j.virol.2017.02.024

Fig 4.

Fig 4

Longitudinal analysis of neutralizing responses in vaccinated rabbits. Changes in serum ID50 titers against four JR-FL variants were followed over the course of immunization of all 4 Study 1 rabbits that generated tier 2 nAbs. The four variants analyzed were JR-FL WT (open symbols) and SOS versions (solid symbols) of the N362Q index (orange) and parent (red) strains. The preceding immunogen boost for each bleed is indicated by arrows. The color scheme matches that used in Figures 2 and 3.