Table 2. Cochrane Risk of Bias Ratings for Included Trials.

Study	Random Sequence Generation (Selection Bias)	Allocation Concealment (Selection Bias)	Blinding of Participants and Personnel (Performance Bias)	Blinding of Outcome Assessment (Detection Bias)	Incomplete Outcome Data (Attrition Bias)	Selective Reporting (Reporting Bias)
Bieryla and Dold23	Unclear risk	Unclear risk	High risk	High risk	High risk	Unclear risk
Cho et al24	Unclear risk	Unclear risk	High risk	Unclear risk	Unclear risk	Unclear risk
Duqu et al32	Unclear risk	Unclear risk	High risk	Low Risk	Unclear risk	High risk
Franco et al26	Low Risk	High risk	High risk	High risk	Low Risk	Unclear risk
Jorgensen et al27	Low Risk	Low Risk	Low Risk	Low Risk	Low Risk	Low Risk
Lai et al25	Unclear risk	Unclear risk	High risk	Unclear risk	Unclear risk	Unclear risk
Laver et al28	Low Risk	Low Risk	High risk	Low Risk	Low Risk	Unclear risk
Lee et al29	Unclear risk	Unclear risk	High risk	Unclear risk	Low Risk	Unclear risk
Maillot et al30	Unclear risk	Unclear risk	High risk	Unclear risk	High risk	Unclear risk
Pichierri et al31	Low Risk	Unclear risk	High risk	Unclear risk	Unclear risk	Low Risk
Pichierri et al33	Low Risk	Unclear risk	High risk	High risk	High risk	Unclear risk
Pluchino et al34	Low Risk	Low Risk	High risk	Unclear risk	High risk	Unclear risk
Ray et al35	Unclear risk	Unclear risk	High risk	Unclear risk	Unclear risk	Unclear risk
Rendon et al36	Unclear risk	Unclear risk	High risk	Unclear risk	Low Risk	Unclear risk
Sato et al37	Low Risk	Unclear risk	High risk	Unclear risk	Low Risk	Unclear risk
Schoene et al38	Low Risk	Low Risk	High risk	Low Risk	Low Risk	Low Risk
Szturm et al39	Unclear risk	Unclear risk	High risk	Low Risk	Low Risk	Low Risk
Toulotte et al40	Unclear risk	Unclear risk	High risk	Unclear risk	Low Risk	High risk