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. 2018 Jan 9;159(4):739–748. doi: 10.1097/j.pain.0000000000001137

Figure 4.

Figure 4.

Effect of hyaluronan (Synvisc) on nocifensive responses developed after MSU-evoked inflammation. Data of all parameters are expressed as % of the values measured 3 hours after amorphous (black, n = 17) or needle MSU (blue, n = 15) injection, represented by the empty bars. (A) Joint diameter, (B) weight-bearing asymmetry, (C) mechanical threshold, and (D) acetone (cold) sensitivity. Values were measured 2 and 5 hours after Synvisc injection (red bars n = 10, after amorphous MSU, n = 7, after needle MSU). Paired t test ***P < 0.001, **P < 0.01, *P < 0.05. MSU, monosodium urate.