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. 2018 Mar 20;41(3):125–129. doi: 10.1097/CJI.0000000000000208

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Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/

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LM replicates in tumors. The Gram (A) and Hematoxylin and eosin stainings (B) of B16F10-Ova tumors 24 hours after injection. C, Immunohistochemistry analysis of caspase-3 cleavage in B16F10-Ova tumors 48 hours after LM treatment. Serum from the same animals were collected and LDH (D) and HMGB1 (E) concentrations were measured. Unpaired 2-tailed t test with the Welch correction (**P<0.01). LM indicates Listeria monocytogenes; Ova, ovalbumin; HMGB1, high mobility group box 1 protein; LDH, Lactate dehydrogenase.