Skip to main content
. Author manuscript; available in PMC: 2018 Apr 11.
Published in final edited form as: Annu Rev Biophys. 2013;42:217–239. doi: 10.1146/annurev-biophys-083012-130404

Figure 6.

Figure 6

Molecular assemblies in RNAi. (a) The interface between the C-terminal portion of PABPC1 and the DUF of TNRC6C, a GW protein (PDB ID: 2X04). Interacting side chains are shown as sticks. (b) The human endonuclease C3PO comprises hetero- and homodimers of Trax (yellow) and/or Translin (green or teal). The teal-colored Translin homodimer in the foreground is partially cut away to reveal the side chains of Trax’s active site, rendered as sticks. In this crystal structure, the complex adopts a hollow, egg-like shape with no obvious means for its passenger strand substrate to access the enclosed active sites (PDB ID: 3PJA).