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. 2018 Mar 30;97(13):e0132. doi: 10.1097/MD.0000000000010132

Figure 2.

Figure 2

MyD88/NFκB was associated with the thrombosis process. (A) Representative Western blot and (B–E) quantitative Western blot analysis of LAAs from patients underwent valve replacement of SR group (n = 15), AF(+)T(−) group (n = 15), AF(+)T(+) group (n = 15) using antibodies against TLR4, RAGE, MyD88, p-NFκB, NFκB, and GAPDH as loading control. Measurements of individual samples were done in duplicate. (F–K) Representative immunohistochemical staining of HMGB1, TLR4, RAGE, TF in SR group, AF(+)T(−) group, AF(+)T(+) group. Arrows indicate TLR4 and RAGE protein. Bar = 50 μm. AF = atrial fibrillation, GAPDH = glyceraldehyde-3-phosphate dehydrogenase, LAAs = left atrial appendages, RAGE = advanced glycation end product, SR = sinus rhythm, T = thrombus, TF = tissue factor, TLRs = Toll-like receptors,.