Table 1.

Patient inclusion and exclusion criteria for study participation

Inclusion: Histologically-proven stage I–III colon cancer Completed cancer treatment(s) within 36 months of entering the study Self-reported participation of ≤150 min·wk−1 of moderate or vigorous intensity physical activity using the Paffenbarger Physical Activity Questionnaire (46) Age ≥18 years Provided written physician approval No additional surgery planned within the six month intervention period The ability to walk unaided for six minutes

Exclusion: History of another primary cancer (other than non-melanoma skin cancer) Evidence of distant metastatic disease Pregnant or breast feeding Unable to provide a baseline blood sample Myocardial infarction or coronary revascularization procedure within the past three months Uncontrolled hypertension (systolic blood pressure ≥180 mm Hg or diastolic blood pressure ≥100 mm Hg) High-risk or uncontrolled cardiac arrhythmias Clinically significant heart valve disease Decompensated heart failure A known aortic aneurysm Any other condition which, in the opinion of the investigator, may impede testing of study hypotheses or make it unsafe to engage in the exercise program